Digital health technologies, applications, and electronic platforms are ever increasing in the healthcare space with significant promise in improving care and outcomes for vulnerable populations that historically have faced access challenges and gaps in care, such as AYA Cancer. Considerations for the AYA, AYA-Oncology trainee education, development of AYA oncology nursing expertise, and physicians who care for AYA are included. In addition to leveraging digital communication in AYA cancer care, key issues of focus will include sleep and fatigue and bridging unmet supportive care needs for AYAs with Cancer.